URED1_STRGG
ID URED1_STRGG Reviewed; 255 AA.
AC B1VNN9;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Urease accessory protein UreD 1 {ECO:0000255|HAMAP-Rule:MF_01384};
GN Name=ureD1 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=SGR_233;
OS Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces.
OX NCBI_TaxID=455632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 4626 / NBRC 13350;
RX PubMed=18375553; DOI=10.1128/jb.00204-08;
RA Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA Yamashita A., Hattori M., Horinouchi S.;
RT "Genome sequence of the streptomycin-producing microorganism Streptomyces
RT griseus IFO 13350.";
RL J. Bacteriol. 190:4050-4060(2008).
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
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DR EMBL; AP009493; BAG17062.1; -; Genomic_DNA.
DR RefSeq; WP_012377636.1; NC_010572.1.
DR AlphaFoldDB; B1VNN9; -.
DR SMR; B1VNN9; -.
DR STRING; 455632.SGR_233; -.
DR EnsemblBacteria; BAG17062; BAG17062; SGR_233.
DR GeneID; 6214450; -.
DR KEGG; sgr:SGR_233; -.
DR PATRIC; fig|455632.4.peg.212; -.
DR eggNOG; COG0829; Bacteria.
DR HOGENOM; CLU_089314_0_0_11; -.
DR OMA; RMLWRDT; -.
DR OrthoDB; 1764668at2; -.
DR Proteomes; UP000001685; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR HAMAP; MF_01384; UreD; 1.
DR InterPro; IPR002669; UreD.
DR Pfam; PF01774; UreD; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion.
FT CHAIN 1..255
FT /note="Urease accessory protein UreD 1"
FT /id="PRO_0000346607"
SQ SEQUENCE 255 AA; 27376 MW; 33E6A5241DAAC770 CRC64;
MTGPPAPAAR PAEPDDPTVV AVERDASGRH LARELSPGAF LAPRPLLPCA DRLRIALVGT
RAGLLAGDDL RLHVSVGPGA RLDLVEPSGL VAYDHRGGRS AWRARIDIAA GGRLDWDGKP
FVVAHGAWVD RTMEVTLAPG ARMLWRDTLV LGRSGERGGR VRTRTRAEYD GRELLVEDLD
LTDPDIRELP GVLGPNRIVG SVTALGTRPP GPPHPYRTDL AGPGAQVRLL DTEAPAMEAE
LSALCEHWRT ENDHA