ID   URED2_METPB             Reviewed;         297 AA.
AC   B1ZHP3;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Urease accessory protein UreD 2 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD2 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Mpop_3209;
OS   Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
OS   (Methylobacterium populi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=441620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-705 / NCIMB 13946 / BJ001;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Marx C., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium populi BJ001.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACB81361.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP001029; ACB81361.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; B1ZHP3; -.
DR   SMR; B1ZHP3; -.
DR   STRING; 441620.Mpop_3209; -.
DR   EnsemblBacteria; ACB81361; ACB81361; Mpop_3209.
DR   KEGG; mpo:Mpop_3209; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   Proteomes; UP000007136; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..297
FT                   /note="Urease accessory protein UreD 2"
FT                   /id="PRO_0000346576"
SQ   SEQUENCE   297 AA;  31721 MW;  0B4AE5F063FB6A4A CRC64;
     MSEEAWARSA GGRAILAESP RPVPSRQRSN GVVRLRVARA GIAADGPTRI VDLAEGGPLR
     LRFPRQGAER MLEGVLVNTG GGVACGDVFE VSVMVEAGAA CLLTTTAAEK IYRSDGANAT
     ILNRIEVGPA GRLDWLPQET ILFDRARLVR RFEADLAPDA SLLVAEIAVL GRAARGERLE
     QALFEDRWRI RRGGRLVYAD SLRLDGAVSD LMARAATGGG ARALATLLDL APGAEARLDE
     ARTLLDALPA GVEAGASAWN GHLAVRMLAP AIAPLREAAA RFLAVWRDRP MPRVWQS