ID   URED2_PSEU2             Reviewed;         281 AA.
AC   Q4ZN11;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Urease accessory protein UreD 2 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD2 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Psyr_4431;
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a;
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT   syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000075; AAY39461.1; -; Genomic_DNA.
DR   RefSeq; WP_011269030.1; NC_007005.1.
DR   RefSeq; YP_237499.1; NC_007005.1.
DR   AlphaFoldDB; Q4ZN11; -.
DR   SMR; Q4ZN11; -.
DR   STRING; 205918.Psyr_4431; -.
DR   EnsemblBacteria; AAY39461; AAY39461; Psyr_4431.
DR   KEGG; psb:Psyr_4431; -.
DR   PATRIC; fig|205918.7.peg.4573; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..281
FT                   /note="Urease accessory protein UreD 2"
FT                   /id="PRO_0000340494"
SQ   SEQUENCE   281 AA;  31011 MW;  7D46CA0F7DE4EC5A CRC64;
     MNLPANTALF TPSWHAELEL GYGRFDDSTR PTLRRHKGPL RVQKHLYAEG PEVCQHIIVH
     PPGGIAGGDR LDISATVGAD AWAQLTSPGA AKWYRAASPA FQQLELHVQP GATLEWLPQE
     SIVFSNAQAE LSTRIELHGD AKLCYWDVVA LGRPASGERF EHGHFQSHLD IRRDGTLLWH
     ERQRIIGGDG LLDSPIGLDG RTVFATLLMT GEVGSELLEA CRSLSMPNPV RGDLTQLPGL
     LVARCLADEA LHARAWLIQI WKCLRPALLG REAVTPRIWN T