ID   URED3_BRASB             Reviewed;         278 AA.
AC   A5ERV4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Urease accessory protein UreD 3 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD3 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=BBta_7013;
OS   Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=288000;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTAi1 / ATCC BAA-1182;
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA   Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E.,
RA   Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA   Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000494; ABQ38898.1; -; Genomic_DNA.
DR   RefSeq; WP_012046828.1; NC_009485.1.
DR   AlphaFoldDB; A5ERV4; -.
DR   SMR; A5ERV4; -.
DR   STRING; 288000.BBta_7013; -.
DR   EnsemblBacteria; ABQ38898; ABQ38898; BBta_7013.
DR   KEGG; bbt:BBta_7013; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   OMA; MARFCAQ; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000000246; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..278
FT                   /note="Urease accessory protein UreD 3"
FT                   /id="PRO_0000340415"
SQ   SEQUENCE   278 AA;  29636 MW;  D89DC06FB6091CFE CRC64;
     MRADPASAAA DIFEANRARG AVRFDVRLQD GMTRRHHLHE SGSLRVRFPS PEDDGLSAMF
     VNTAGGIAGG DRFAVEVAAG EGSRVTLSSA AAEKVYRAPG KPAELDIALT AAAGAHIAWL
     PQETILFDRA RIHRRIDIDL AATASLLLCE IVVFGRTAMG ERMREGEFVD RWRLRRGGRL
     VFAETVRLDG DIGGKLAHPA IANGAAAIGT ALIVPGDAAL VERIRESLPA FRGEAGLSAW
     NGFAMARFCA QDAASLRADM MAVLGCASAV PLPRLWLN