ID   URED3_BRASO             Reviewed;         280 AA.
AC   A4Z049;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Urease accessory protein UreD 3 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD3 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=BRADO5861;
OS   Bradyrhizobium sp. (strain ORS 278).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=114615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ORS 278;
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA   Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E.,
RA   Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA   Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CU234118; CAL79525.1; -; Genomic_DNA.
DR   RefSeq; WP_012029427.1; NC_009445.1.
DR   AlphaFoldDB; A4Z049; -.
DR   SMR; A4Z049; -.
DR   STRING; 114615.BRADO5861; -.
DR   EnsemblBacteria; CAL79525; CAL79525; BRADO5861.
DR   KEGG; bra:BRADO5861; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_1_5; -.
DR   OMA; PYPFHIT; -.
DR   OrthoDB; 1764668at2; -.
DR   BioCyc; BSP114615:BRADO_RS27275-MON; -.
DR   Proteomes; UP000001994; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..280
FT                   /note="Urease accessory protein UreD 3"
FT                   /id="PRO_0000346557"
SQ   SEQUENCE   280 AA;  28864 MW;  AD5571DE7E1FE6B0 CRC64;
     MRSPLQSCSA SEGRAVEAAL SVDHAGGRSV LRRQNVGYPL HVTRGFHLDA ARPDLLTLYL
     QSASGGLYAG DRIALDVSVA RDAAFHLTTQ AATVVHDGRG IGALQRQTIT VDSGAFCAIT
     TDPYVLFPGA ELALDTVATV ADDAVLCVAD GFAVHDPRAS GRAFSEFSGR LRVLRPDGHL
     LLHDAGRVSG DELHGALGPF AAAANLIIVA PPDRLPSVKS LQQAADGCGA LAGASRAPND
     AGLVLRILAP DGGTLSRATD AAFHVAAAAA LGVTLSRRRK