ID   URED3_METPB             Reviewed;         311 AA.
AC   B1Z8R4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Urease accessory protein UreD 3 {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD3 {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Mpop_5120;
OS   Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
OS   (Methylobacterium populi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=441620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-705 / NCIMB 13946 / BJ001;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Marx C., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium populi BJ001.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP001029; ACB83216.1; -; Genomic_DNA.
DR   RefSeq; WP_012456812.1; NC_010725.1.
DR   AlphaFoldDB; B1Z8R4; -.
DR   SMR; B1Z8R4; -.
DR   STRING; 441620.Mpop_5120; -.
DR   EnsemblBacteria; ACB83216; ACB83216; Mpop_5120.
DR   KEGG; mpo:Mpop_5120; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_0_5; -.
DR   OMA; IPFENAH; -.
DR   Proteomes; UP000007136; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..311
FT                   /note="Urease accessory protein UreD 3"
FT                   /id="PRO_0000346577"
SQ   SEQUENCE   311 AA;  34456 MW;  C954CEF1A0DD917F CRC64;
     MTLHGPLGLL DTARELRGFR TEPAQMRAGA PGKVGRLRLG FSLRDGVSVL HDLYRVAPLL
     VQQALYWDEA MPDLPVCPII SVGGGILQGD RYTIDITVGE GACAHVSTQG ANRIHCMDAN
     YAAQHQNVTV EAGGYLEYLP DVTIPYRGSR FLSRTEIVVA EDATLLYGEM VLAGRKHHHA
     EERFGFDLLS MDVTLRRPGG RKLFAEKILI ERGDPTIAFA AVMRGFDVFA NILCVTPPGT
     AARIKERFET NFSSDAPRAV SGVSRLPNAA GLMLRAVGVE TYDVRNEVRR FWRIVREEVR
     GRPLPAEPYW R