ID   URED_ACIBY              Reviewed;         291 AA.
AC   B0V9P8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=ABAYE2779;
OS   Acinetobacter baumannii (strain AYE).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=509173;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AYE;
RX   PubMed=18350144; DOI=10.1371/journal.pone.0001805;
RA   Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E.,
RA   Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J.,
RA   Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C.,
RA   Weissenbach J., Cruveiller S.;
RT   "Comparative analysis of Acinetobacters: three genomes for three
RT   lifestyles.";
RL   PLoS ONE 3:E1805-E1805(2008).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CU459141; CAM87610.1; -; Genomic_DNA.
DR   RefSeq; WP_001079965.1; NC_010410.1.
DR   AlphaFoldDB; B0V9P8; -.
DR   SMR; B0V9P8; -.
DR   EnsemblBacteria; CAM87610; CAM87610; ABAYE2779.
DR   KEGG; aby:ABAYE2779; -.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000002446; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..291
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_1000145086"
SQ   SEQUENCE   291 AA;  33789 MW;  03C22AFAB3E2EFC3 CRC64;
     MNRIQQTFQT SSAPFWYAQL ELGFCYENSR TIMSHRKHYG PVRVQKMLWP EKTGVCHAII
     VHPPAGIAGG DHLTFQIETE GQAHAVITTP GAGKWYRTNG KQAFQHIYLN VKDDSILEWM
     PQETMLFDGA LAHSETDIHL EQTASFIGWD MLVLGRQARA ENFVQGSYHN QFKLWRKNKL
     LVADTLYFEG GDRWLSSCLG MNNQAVMASF WAVPPEKFRS SFYLEQHIEL IRELIMRMDV
     PVTLTLLEDV LCARFLGNDV RRCHDAFAAI RAKLRRYWFD LDEEFPRIWK T