ID   URED_ALIB4              Reviewed;         250 AA.
AC   A8ESZ6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Abu_0805;
OS   Aliarcobacter butzleri (strain RM4018) (Arcobacter butzleri).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Arcobacteraceae; Aliarcobacter.
OX   NCBI_TaxID=367737;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM4018;
RX   PubMed=18159241; DOI=10.1371/journal.pone.0001358;
RA   Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M.,
RA   Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A.,
RA   Rogosin A., Stanker L.H., Mandrell R.E.;
RT   "The complete genome sequence and analysis of the Epsilonproteobacterium
RT   Arcobacter butzleri.";
RL   PLoS ONE 2:E1358-E1358(2007).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000361; ABV67070.1; -; Genomic_DNA.
DR   RefSeq; WP_012012547.1; NC_009850.1.
DR   AlphaFoldDB; A8ESZ6; -.
DR   SMR; A8ESZ6; -.
DR   STRING; 367737.Abu_0805; -.
DR   EnsemblBacteria; ABV67070; ABV67070; Abu_0805.
DR   KEGG; abu:Abu_0805; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_1109636_0_0_7; -.
DR   OMA; FNDNENY; -.
DR   OrthoDB; 1228084at2; -.
DR   Proteomes; UP000001136; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..250
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346549"
SQ   SEQUENCE   250 AA;  29880 MW;  752639EEE8748560 CRC64;
     MSIKFSFKDE VFSLDKLQLP SRHYHFNDNE NYIKLLNIGE GIFPKDKIRT SLSLDNSNLI
     FTTESATKIY PSKKEYGIQK IDIVLKNNSN LEFINDELIL YKDSRYIQFF NLKSDENSTF
     FYTDILSRGR SFENFDFSNM LIKNSFFCEK SMEYMEKFDV KGAELKDYIN RKSSSNFIFA
     KIYIKTNNNE EFLNRIYLEK FESFTYTKNK KIILGVISSN NMFELKNQIF KIWELYRKEL
     NKSKFNLGKQ