ID   URED_ARTS2              Reviewed;         293 AA.
AC   A0JRH8;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 2.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Arth_0247;
OS   Arthrobacter sp. (strain FB24).
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=290399;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB24;
RX   PubMed=24501649; DOI=10.4056/sigs.4438185;
RA   Nakatsu C.H., Barabote R., Thompson S., Bruce D., Detter C., Brettin T.,
RA   Han C., Beasley F., Chen W., Konopka A., Xie G.;
RT   "Complete genome sequence of Arthrobacter sp. strain FB24.";
RL   Stand. Genomic Sci. 9:106-116(2013).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK01648.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000454; ABK01648.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A0JRH8; -.
DR   SMR; A0JRH8; -.
DR   STRING; 290399.Arth_0247; -.
DR   EnsemblBacteria; ABK01648; ABK01648; Arth_0247.
DR   KEGG; art:Arth_0247; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_5_0_11; -.
DR   Proteomes; UP000000754; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..293
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346550"
SQ   SEQUENCE   293 AA;  31719 MW;  7871CF3AF735D282 CRC64;
     MSTTAAPEVE LVETETPMGE LALRVAVRGC RSVAAHQYHR GALRILRPHY LDDSGQVCYV
     VVNPGGAYLG ADLYVIDVEV GDGAKLLLTT QSATKIYRTP GSFAEQRVCL RLGEGAQLEL
     APDQLIAYRE ASYRQNTRIT VRPSSSLVMA EVVTPGWSPD GASFRYEELR LRNEIQVETP
     GGTGLLALDN LLIRPPLNDV TGMGFMEGYS HLGSLVVVDA RVEQALADEF HALTAGHDAC
     TGVSLTASVG GTTGLVLRSL SNSTEELNRL LGACTALLRE RWYGQSPLNL RKY