ID   URED_BACC1              Reviewed;         273 AA.
AC   Q733K0;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=BCE_3658;
OS   Bacillus cereus (strain ATCC 10987 / NRS 248).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=222523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10987 / NRS 248;
RX   PubMed=14960714; DOI=10.1093/nar/gkh258;
RA   Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L.,
RA   Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F.,
RA   Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
RT   "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic
RT   adaptations and a large plasmid related to Bacillus anthracis pXO1.";
RL   Nucleic Acids Res. 32:977-988(2004).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AE017194; AAS42563.1; -; Genomic_DNA.
DR   RefSeq; WP_000841917.1; NC_003909.8.
DR   AlphaFoldDB; Q733K0; -.
DR   SMR; Q733K0; -.
DR   PRIDE; Q733K0; -.
DR   EnsemblBacteria; AAS42563; AAS42563; BCE_3658.
DR   GeneID; 59155870; -.
DR   KEGG; bca:BCE_3658; -.
DR   HOGENOM; CLU_056339_5_0_9; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000002527; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..273
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346551"
SQ   SEQUENCE   273 AA;  31567 MW;  366700379CE75B8D CRC64;
     MKSPTGVLNI DVMEKRDKTV PIKVYHKDAL KVTQPIYLDK YGRAYYYIMN SGGGYLKGDF
     YSININVGKD AKTYITSQSA TKVYKTPNSY ALQELNFYIG QNAAMEYLPD PLIMYKDAAY
     KQKTNIYMQN NSTLILCDSV TPGWSPNMEK FTYQYFDSLT KIYMENKLVV YDHLLLNPFK
     ESLDQMGILN QYSHYGTFIV INENVTNDLI AALKTSFSNT NNMKIGIAST TCKGFVIRIL
     SHNTEDMESI FFQCHRFVRE NCLHEELTSY RKY