ID   URED_BACSB              Reviewed;         271 AA.
AC   Q07400;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
OS   Bacillus sp. (strain TB-90).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=36824;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8288539; DOI=10.1128/jb.176.2.432-442.1994;
RA   Maeda M., Hidaka M., Nakamura A., Masaki H., Uozumi T.;
RT   "Cloning, sequencing, and expression of thermophilic Bacillus sp. strain
RT   TB-90 urease gene complex in Escherichia coli.";
RL   J. Bacteriol. 176:432-442(1994).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; D14439; BAA03329.1; -; Genomic_DNA.
DR   PIR; G36950; G36950.
DR   AlphaFoldDB; Q07400; -.
DR   SMR; Q07400; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..271
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000067606"
SQ   SEQUENCE   271 AA;  30947 MW;  23C1569D67F353DD CRC64;
     MKCTGVLQLS AAKKRQKTII SSCYHEGALK VSRPIYLEKD LPFLYLIHVG GGYVDGDVYL
     TNLDVEEEAE LAVTTQSATK VYKTPKKPVV QQTNIHLKKG SVLEYLLDPL ISYKGARFIQ
     ETTVHIEEDS GFFYSDVITP GWAEDGSLFP YDWIRSKLKV YKKDRLVLFD HLRLEPDEDM
     SGMLQMDGYT HIGTFLIFHQ KADKTFLDRL YDEMEAFDSD VRFGMTSLPA SGIILRILAR
     STGIIENMIS RAHSFARREL LGKNGVTWRK Y