ID   URED_BLOFL              Reviewed;         286 AA.
AC   Q7VRS3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Bfl526;
OS   Blochmannia floridanus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=203907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12886019; DOI=10.1073/pnas.1533499100;
RA   Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F.,
RA   Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B.,
RA   van Ham R.C.H.J., Gross R., Moya A.;
RT   "The genome sequence of Blochmannia floridanus: comparative analysis of
RT   reduced genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; BX248583; CAD83212.1; -; Genomic_DNA.
DR   RefSeq; WP_011126789.1; NC_005061.1.
DR   AlphaFoldDB; Q7VRS3; -.
DR   SMR; Q7VRS3; -.
DR   STRING; 203907.Bfl526; -.
DR   EnsemblBacteria; CAD83212; CAD83212; Bfl526.
DR   KEGG; bfl:Bfl526; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000002192; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..286
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340412"
SQ   SEQUENCE   286 AA;  32282 MW;  FB48F4FC93208374 CRC64;
     MFNGFDQGDF LSKSSDDWIS RLELNFVLQE GCSVLKKISH IGPILVQKIF YPENDKSNIP
     HVYLLQPSGG LVGGDQIHIS VCLESGSKVL LTTPGSTKFY RTNGKYILQE HIFKLKDNTS
     LEWLPQSSIF FPNTKVKINT IFHLEPGARI IIGEILCFGS DGWLDNYGSP DVIDIFLRIC
     LPYCSGLRDR LKIDSQNYID KLHGFKISAS LFAAPSNKET LKVVRSLITS TVDIQIGGVT
     LIDELLVVRL LSNNNQRIKE LLYHIWSVIR PIIIGQEAVM PRVWFT