ID   URED_BLOPB              Reviewed;         278 AA.
AC   Q492E6;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=BPEN_545;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BPEN;
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000016; AAZ41155.1; -; Genomic_DNA.
DR   RefSeq; WP_011283066.1; NC_007292.1.
DR   AlphaFoldDB; Q492E6; -.
DR   SMR; Q492E6; -.
DR   STRING; 291272.BPEN_545; -.
DR   EnsemblBacteria; AAZ41155; AAZ41155; BPEN_545.
DR   KEGG; bpn:BPEN_545; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   BioCyc; CBLO291272:BPEN_RS02690-MON; -.
DR   Proteomes; UP000007794; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..278
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340413"
SQ   SEQUENCE   278 AA;  31605 MW;  E032240F6CBA69CE CRC64;
     MSDELSQNFI DGWLGELRLN FALRGGRSVL TRCKHVGPFY VKKVFYSEND NTPHVYLLHP
     PGGLVGGDKL VLDVKLESDS RVLLTTPGAA KFYRSNGLYS EQKHIFRLER NTALEWVPQS
     SIFFPKSKAK IDTTFIIEQG SRVISFDMLC FGNLSLGSST YPEEVDIHLN ICLSDSIGLQ
     ERLRINELNC VMKLGGFRIS ALLFAVPSDE KTLYKVRKLI TSVKHFQVGG ATLLDEILVV
     RLLGNDNQYL KKMLHHIWYT IRPFIIGKKA MLPRIWLT