ID   URED_BRADU              Reviewed;         276 AA.
AC   Q89UG4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=blr1453;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; BA000040; BAC46718.1; -; Genomic_DNA.
DR   RefSeq; NP_768093.1; NC_004463.1.
DR   RefSeq; WP_011084270.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89UG4; -.
DR   SMR; Q89UG4; -.
DR   STRING; 224911.27349705; -.
DR   PRIDE; Q89UG4; -.
DR   EnsemblBacteria; BAC46718; BAC46718; BAC46718.
DR   GeneID; 64021331; -.
DR   KEGG; bja:blr1453; -.
DR   PATRIC; fig|224911.44.peg.884; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   InParanoid; Q89UG4; -.
DR   OMA; MARFCAQ; -.
DR   PhylomeDB; Q89UG4; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..276
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340414"
SQ   SEQUENCE   276 AA;  29475 MW;  84A56EFBE9D3C007 CRC64;
     MRSELSVTSS IFEANRARGA VRFDVHARDG VTRRGVLHES GSLRVRFPSP EDEGLSGVFV
     NTAGGVAGGD RFDVEISAAD AARLTLTTAA AEKVYRAPGP AAELNIALKV GAGAHLSWLP
     QETILFDRAR VHRRFDIALD EAASLLLCEI VVFGRTAMGE RMEQGEFVDR WRLSRGGRLV
     FAETVRLGGD IGAKLARSAV AKGGAAIGTA LIVPGDEALI ERIREASESF AGEVGISAWN
     GFAMARFCAQ DAARLRADMM AVLARTGAAL PRLWLN