ID   URED_BURCM              Reviewed;         291 AA.
AC   Q0BHN2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Bamb_0782;
OS   Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia
OS   (strain AMMD)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=339670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-244 / AMMD;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Bruce D., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Parke J., Coenye T., Konstantinidis K.,
RA   Ramette A., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia cepacia AMMD.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000440; ABI86341.1; -; Genomic_DNA.
DR   RefSeq; WP_011656158.1; NZ_CP009798.1.
DR   AlphaFoldDB; Q0BHN2; -.
DR   SMR; Q0BHN2; -.
DR   STRING; 339670.Bamb_0782; -.
DR   EnsemblBacteria; ABI86341; ABI86341; Bamb_0782.
DR   GeneID; 44691463; -.
DR   KEGG; bam:Bamb_0782; -.
DR   PATRIC; fig|339670.21.peg.810; -.
DR   eggNOG; COG0829; Bacteria.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000000662; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..291
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340430"
SQ   SEQUENCE   291 AA;  30859 MW;  8F044C9BDBAEA54F CRC64;
     MSAPDSHASL SRPSVAKSWR GRLELGFERH GARTTLVHRL HDGPLRVQRP LYPEGDAICH
     AVIVHPPGGV AGGDQLDIGI ALGDGTHAVL TTPGATKWYK SNGLDATQRI GITVGAHAKL
     DWLPQNNLFF DAAHAALDFT VTLGAGASAI GWDATQLGRQ AAGETWSAGR IASRSALVDA
     DGRPLWTERA LLDAHDPLRG ALQGLAGFPV YGTLWAAGAA CDAALAEALA ARMPFDDTLR
     AGATCVTPGV VLVRALSTSM EALQRHFADC WLYLRPIVHG VDARPLRLWQ T