ID   URED_CENSY              Reviewed;         285 AA.
AC   A0RUR7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=CENSYa_0450;
OS   Cenarchaeum symbiosum (strain A).
OC   Archaea; Thaumarchaeota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX   NCBI_TaxID=414004;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A;
RX   PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA   Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA   Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT   "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT   symbiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; DP000238; ABK77084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0RUR7; -.
DR   SMR; A0RUR7; -.
DR   STRING; 414004.CENSYa_0450; -.
DR   EnsemblBacteria; ABK77084; ABK77084; CENSYa_0450.
DR   KEGG; csy:CENSYa_0450; -.
DR   PATRIC; fig|414004.10.peg.409; -.
DR   HOGENOM; CLU_056339_1_0_2; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000000758; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..285
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340535"
SQ   SEQUENCE   285 AA;  30676 MW;  FF2AA1AAD381749F CRC64;
     MGQLGVGRTG KTAVLDIELR RSGSRTIISR QYSEVPLQVQ RALYPDAGLP GMAHVYVLSP
     SGGLLQGDRY KTSISLKDKA AAHVTTQGAS RIYGMNSNCA IHKMDISAGK GCYLEYIPDQ
     VIPYAKSRYF QEVRLAIDDD AAAVYSEVVT PGRVAMGESF LYDILCTSVR CENQDGSLRF
     AENARAEPRR MNLRGEAVLG GYSVHGTVYV MAPPESARTI EYTAGRIISH TDGILGGTSL
     LPGGAGITAR LLSHRTDSIF KCIEGIAGAC RMEMTGAAYP GIRKC