ID   URED_CERS5              Reviewed;         275 AA.
AC   A4WR71;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   OrderedLocusNames=Rsph17025_0984;
OS   Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=349102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17025 / ATH 2.4.3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Richardson P., Mackenzie C., Choudhary M.,
RA   Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome of Rhodobacter sphaeroides ATCC 17025.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000661; ABP69885.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4WR71; -.
DR   SMR; A4WR71; -.
DR   STRING; 349102.Rsph17025_0984; -.
DR   EnsemblBacteria; ABP69885; ABP69885; Rsph17025_0984.
DR   KEGG; rsq:Rsph17025_0984; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   OMA; MARFCAQ; -.
DR   OrthoDB; 1764668at2; -.
DR   BioCyc; RSPH349102:G1G8M-1010-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..275
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340506"
SQ   SEQUENCE   275 AA;  28940 MW;  8496B5C953C875C0 CRC64;
     MNALTPPRDC LERSQGHAQV TLARVLGAVR LRDLAQRGSA KAFLPRVDGP VPEIVFLNTS
     GGLTGGDRLS YRLEVGEGCR AVATTQTAER AYAAGRGVAQ VRVAHEVGAG GWLDWLPQET
     ILFEDSALDR RTEIVLGPGA GCLMVESVVL GRAAMGETLS RLAFRDLRQI TRGGRPVLVE
     PLALDDRALA AAAGAAVLGG LRALATLALV GPGAEDALGP ARAVLDEPGV EAAASAFDGK
     LLVRMLALDG WPLRRQVARV LGVLRGRALP RVWQD