ID   URED_COREF              Reviewed;         282 AA.
AC   Q8FQW8;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=CE0999;
OS   Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS   / NBRC 100395).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA   Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC17809.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000035; BAC17809.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q8FQW8; -.
DR   SMR; Q8FQW8; -.
DR   STRING; 196164.23492837; -.
DR   EnsemblBacteria; BAC17809; BAC17809; BAC17809.
DR   KEGG; cef:CE0999; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_5_0_11; -.
DR   Proteomes; UP000001409; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..282
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340447"
SQ   SEQUENCE   282 AA;  30949 MW;  225F17D7D56EE9C5 CRC64;
     MKPGGELRLR IAHRGTDGRS FAQSQFHRGA LRVLRPHYPS DDGLVSYTLI NPGGGFLGGD
     VYDIDVEVGD GAGLQLCTQS ATKIYRTPQG PAVQQTVVKL GKRALLESVP DPVIVYRGGT
     YRQSTRVEMD ESSVFLSAEI VTPGWSPDAT HFGFDRLHMR TEVMMQGRMV LLDNLRMVPD
     VDISGIGVME GFSHSGTLIL IAPPLCNDVV FHAATNIVES VRWSGVGELE CGLTRVHGGF
     VVRSLAYRSG RIQQIHEAII ELYRHETAKW RGAESASSMH YS