ID   URED_CORGB              Reviewed;         283 AA.
AC   A4QA27;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=cgR_0109;
OS   Corynebacterium glutamicum (strain R).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=340322;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R;
RX   PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA   Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M.,
RA   Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT   "Comparative analysis of the Corynebacterium glutamicum group and complete
RT   genome sequence of strain R.";
RL   Microbiology 153:1042-1058(2007).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AP009044; BAF53070.1; -; Genomic_DNA.
DR   RefSeq; WP_011896414.1; NC_009342.1.
DR   AlphaFoldDB; A4QA27; -.
DR   SMR; A4QA27; -.
DR   EnsemblBacteria; BAF53070; BAF53070; cgR_0109.
DR   KEGG; cgt:cgR_0109; -.
DR   HOGENOM; CLU_056339_5_0_11; -.
DR   OMA; CQHIIVH; -.
DR   PhylomeDB; A4QA27; -.
DR   Proteomes; UP000006698; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..283
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_1000145088"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  31746 MW;  BBE435331C3702AE CRC64;
     MTQTQPVGTL RLTIDDQGPQ GQSRAVEQFH QGALRVIRPH YLDDSGQVSY TIIAIGGGYL
     GGDVYEQQFT VKDNAKALIT TQSATKIYRT PQGPVTQYTE INVGENAVLE YLADQTIAYR
     ESTYHQFTKV TLHPTSTFVM SEQITPGWHP DGKHFAYDEM RLHTEITDST TGRLVLLDNL
     LLRPDSREGS FGWTEQYTHS GQMIVMGEGV DKQLVAELNE QLAAHPDVYG AVNFLSAPGT
     LLRGFIARTL SNRTEELINL HEHIASLLRG RWRGQEPVNL RKY