ID   URED_HERA2              Reviewed;         287 AA.
AC   A9AZE9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Haur_2455;
OS   Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95).
OC   Bacteria; Chloroflexi; Chloroflexia; Herpetosiphonales; Herpetosiphonaceae;
OC   Herpetosiphon.
OX   NCBI_TaxID=316274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23779 / DSM 785 / 114-95;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Bryant D.A., Richardson P.;
RT   "Complete sequence of chromosome of Herpetosiphon aurantiacus ATCC 23779.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000875; ABX05093.1; -; Genomic_DNA.
DR   AlphaFoldDB; A9AZE9; -.
DR   SMR; A9AZE9; -.
DR   STRING; 316274.Haur_2455; -.
DR   EnsemblBacteria; ABX05093; ABX05093; Haur_2455.
DR   KEGG; hau:Haur_2455; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_5_1_0; -.
DR   OMA; LMVFIVN; -.
DR   Proteomes; UP000000787; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..287
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346568"
SQ   SEQUENCE   287 AA;  32447 MW;  48C08E8B0EEF07E9 CRC64;
     MQTATRLERM HGHLALDFTL KQQRTRLTVR EHRPPLQVVR DFGLADGTSF VHLHNVAGGV
     LAGDQLTTTI KLAASTKAQL TTTSSTRIYR SDGEQIAYQQ VQATLAEQSL LEYWPDTTIP
     FAESLYQQQT RIDLAADAGL CWWEFLAPGR EAYGERFAYR QLRLDCDIYA LGRPILLDRM
     RLQPSLQQLS NPLYFGKYSY LATGYICRVG WDAVQWKALE AELMAFAASQ TKLGRCLWGV
     SCLAAHGLVI RGLSSNSRDL LATAFDYWRF AKQALYGTTP NLPRKIY