ID   URED_JANMA              Reviewed;         296 AA.
AC   A6SZ04;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=mma_1811;
OS   Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Janthinobacterium.
OX   NCBI_TaxID=375286;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Marseille;
RX   PubMed=17722982; DOI=10.1371/journal.pgen.0030138;
RA   Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D.,
RA   Drancourt M.;
RT   "Genome analysis of Minibacterium massiliensis highlights the convergent
RT   evolution of water-living bacteria.";
RL   PLoS Genet. 3:1454-1463(2007).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000269; ABR89778.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6SZ04; -.
DR   SMR; A6SZ04; -.
DR   STRING; 375286.mma_1811; -.
DR   EnsemblBacteria; ABR89778; ABR89778; mma_1811.
DR   KEGG; mms:mma_1811; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_4; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000006388; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..296
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340457"
SQ   SEQUENCE   296 AA;  32386 MW;  6AE1EB6352C84562 CRC64;
     MKRLSDTSSA ITHTNKSGIA SFRNDQARLS LAFTDDAGTT RMTERSHFGP LRVQKTLYPE
     HPAVCHAIIV HPPGGIVGGD QLTITARVGD RAHALLTTPG AGKWYRANGQ LSQQQVSLEV
     GADAALEWLP QETIFFNEAD VRLEHNVTLA ADARYIGGEI LCFGRTASGE TFDSGRVAQR
     TSIRRGGKLL WFEQGALQAR STSMHSPLSL AGYTVCATLI AVGKTMNGAF LNELREESSA
     LAQGGRSGAT QMKQVLVARY LGHSSETARL WMTRAWQRIR PELMQRDAVI PRIWNT