URED_JANSC
ID URED_JANSC Reviewed; 266 AA.
AC Q28RK1;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Jann_1744;
OS Jannaschia sp. (strain CCS1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia; unclassified Jannaschia.
OX NCBI_TaxID=290400;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCS1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J.,
RA Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W.,
RA Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABD54661.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000264; ABD54661.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_044006567.1; NC_007802.1.
DR AlphaFoldDB; Q28RK1; -.
DR SMR; Q28RK1; -.
DR STRING; 290400.Jann_1744; -.
DR EnsemblBacteria; ABD54661; ABD54661; Jann_1744.
DR KEGG; jan:Jann_1744; -.
DR eggNOG; COG0829; Bacteria.
DR HOGENOM; CLU_056339_2_0_5; -.
DR OrthoDB; 1764668at2; -.
DR Proteomes; UP000008326; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR HAMAP; MF_01384; UreD; 1.
DR InterPro; IPR002669; UreD.
DR PANTHER; PTHR33643; PTHR33643; 1.
DR Pfam; PF01774; UreD; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT CHAIN 1..266
FT /note="Urease accessory protein UreD"
FT /id="PRO_0000340456"
SQ SEQUENCE 266 AA; 28657 MW; A27AE7D3FB51D6C3 CRC64;
MLDAATPTHQ RVRGRAMARF TGRRLRDLHQ SGSAKVLIPR VFGRAPEVVF LNTAGGITGG
DRLDYALHVD DGTCVGTTQT AERAYRSHGP MGRVSTRLTI GQGATLHWVP QEMILFDGVA
LERDLSVEMA GDAELVMLET LVLGRAAMGE VLRDLHLRDR RRVTRGGKLA MVEAIGLGPD
DFASSSPAGL NGAVATASLT LMAQDAEDRL NALRAVLPTD VRSAASAWDG RLTARFLAPQ
AYPLRRAVAR AVEQVTCGAL PRVWQI