ID   URED_LYSSC              Reviewed;         268 AA.
AC   B1HZE8;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 2.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Bsph_2705;
OS   Lysinibacillus sphaericus (strain C3-41).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX   NCBI_TaxID=444177;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C3-41;
RX   PubMed=18296527; DOI=10.1128/jb.01652-07;
RA   Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M.,
RA   Berry C., Yuan Z.;
RT   "Complete genome sequence of the mosquitocidal bacterium Bacillus
RT   sphaericus C3-41 and comparison with those of closely related Bacillus
RT   species.";
RL   J. Bacteriol. 190:2892-2902(2008).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACA40245.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000817; ACA40245.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_036162731.1; NC_010382.1.
DR   AlphaFoldDB; B1HZE8; -.
DR   SMR; B1HZE8; -.
DR   EnsemblBacteria; ACA40245; ACA40245; Bsph_2705.
DR   KEGG; lsp:Bsph_2705; -.
DR   HOGENOM; CLU_056339_6_0_9; -.
DR   Proteomes; UP000002164; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..268
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346571"
SQ   SEQUENCE   268 AA;  30780 MW;  126D367E72CC8015 CRC64;
     MVNPQKINHF GKLEMAFEPR RGYTRLVHVY QQPPLKASRE LYEGSDPTAT VFLMESSGGM
     VAGDRNEINV KLASGSRVRL KQQSALKIYP SHTGDHCTQA ITVEMADEAR LEWLPEVTIP
     FERAKFQADT TIRMKESSTL IWGEIVAPGR EMRGEVFDYQ AYQSKYKVYV EEQLIAFDSI
     HFKPQEMNFA ALGLLEKALY IGSLWIVSPL VKNLNMRDLQ DLIQQEQSLQ ASVTKLTDQA
     IHCRWLAKEQ RTLHKEINRM FEQMTALL