ID   URED_NITOC              Reviewed;         296 AA.
AC   Q3J767;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Noc_2883;
OS   Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB
OS   11848 / C-107).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC   Nitrosococcus.
OX   NCBI_TaxID=323261;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107;
RX   PubMed=16957257; DOI=10.1128/aem.00463-06;
RA   Klotz M.G., Arp D.J., Chain P.S.G., El-Sheikh A.F., Hauser L.J.,
RA   Hommes N.G., Larimer F.W., Malfatti S.A., Norton J.M., Poret-Peterson A.T.,
RA   Vergez L.M., Ward B.B.;
RT   "Complete genome sequence of the marine, chemolithoautotrophic, ammonia-
RT   oxidizing bacterium Nitrosococcus oceani ATCC 19707.";
RL   Appl. Environ. Microbiol. 72:6299-6315(2006).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000127; ABA59329.1; -; Genomic_DNA.
DR   RefSeq; WP_002813294.1; NC_007484.1.
DR   AlphaFoldDB; Q3J767; -.
DR   SMR; Q3J767; -.
DR   STRING; 323261.Noc_2883; -.
DR   PRIDE; Q3J767; -.
DR   EnsemblBacteria; ABA59329; ABA59329; Noc_2883.
DR   KEGG; noc:Noc_2883; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000006838; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..296
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340466"
SQ   SEQUENCE   296 AA;  32578 MW;  523F0F5949198A96 CRC64;
     MKKIAVFKQM PCEAADAPPA KTDLLPLSWP AKLELGYQRV KMRTVPVLRR HQGPLRVQKH
     LYPEGPAVCQ HMILHPPGGI AGGDTLDIQI HAGSHAWAQL TSPGAAKWYR SEVSLARQNL
     ALSTEPGGIL EWLPQETIFF AGCQTALDTT IDLAEDAKVI AWDIIALGRP ASGERFNSGR
     IYQRFRLRRN GRLLWSERMQ LLGGSRLLES PIGFAGYPVA GTLLASGELN DQQLTACRSL
     PIEGGRGGLS QLPGLVVARF LGEETEAARN WFIALWQELR PALLGRSVSI PRIWNT