ID   URED_NOSS1              Reviewed;         279 AA.
AC   Q8YQZ4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=alr3666;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; BA000019; BAB75365.1; -; Genomic_DNA.
DR   PIR; AC2264; AC2264.
DR   RefSeq; WP_010997810.1; NZ_RSCN01000044.1.
DR   AlphaFoldDB; Q8YQZ4; -.
DR   SMR; Q8YQZ4; -.
DR   STRING; 103690.17132799; -.
DR   PRIDE; Q8YQZ4; -.
DR   EnsemblBacteria; BAB75365; BAB75365; BAB75365.
DR   KEGG; ana:alr3666; -.
DR   eggNOG; COG0829; Bacteria.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..279
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340406"
SQ   SEQUENCE   279 AA;  31291 MW;  40573BCF3C1B7675 CRC64;
     MSETDTIVKG WHGKLNLVYA DRSNSTQLIY NHQQAPLKVQ RPFYPEGEKV CHSVILHTAG
     GVVGGDRLSY NLHLQPNAQA LITTAAAGKV YRSDGLQARQ TIEIKIDAGA CLEWLPQETI
     LFNGAIYRQD LRVELATGAN FLGWEITRFG RSARGEKFYQ GEWRSHTEIW QQGVPLWIDR
     QWLPGNDAVF HSPHGLAGQP IVGSLVWLGS PISTEIIEKA RNLGNTQGEA GVTSLENGFL
     CRYRGASTSE VRNWFTSVWQ LLRGEFFSRG KCIPRVWQT