ID   URED_OPITP              Reviewed;         272 AA.
AC   B1ZNZ6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Oter_4212;
OS   Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1).
OC   Bacteria; Verrucomicrobia; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX   NCBI_TaxID=452637;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11246 / JCM 15787 / PB90-1;
RX   PubMed=21398538; DOI=10.1128/jb.00228-11;
RA   van Passel M.W., Kant R., Palva A., Copeland A., Lucas S., Lapidus A.,
RA   Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J.,
RA   Larimer F.W., Land M.L., Hauser L., Kyrpides N., Mikhailova N.,
RA   Richardson P.P., Janssen P.H., de Vos W.M., Smidt H.;
RT   "Genome sequence of the verrucomicrobium Opitutus terrae PB90-1, an
RT   abundant inhabitant of rice paddy soil ecosystems.";
RL   J. Bacteriol. 193:2367-2368(2011).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP001032; ACB77485.1; -; Genomic_DNA.
DR   RefSeq; WP_012377013.1; NC_010571.1.
DR   AlphaFoldDB; B1ZNZ6; -.
DR   SMR; B1ZNZ6; -.
DR   STRING; 452637.Oter_4212; -.
DR   PRIDE; B1ZNZ6; -.
DR   EnsemblBacteria; ACB77485; ACB77485; Oter_4212.
DR   KEGG; ote:Oter_4212; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_5_0_0; -.
DR   OMA; MHATPRI; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000007013; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..272
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346584"
SQ   SEQUENCE   272 AA;  29708 MW;  ED8B55A346A4931F CRC64;
     MDFAGHLHLR AAPRAFGHTA LTLQSFRAPF HLSKPYWDYD SRVLLVQVVN PTAGILAGDR
     IESEITVDAG AALLITTPSA SRVFRMDAGV ATCRQHFTVA AGAWLEVMPG PLVPHRGSDY
     RQSTIVELTR GAGGFFVDQL MPGRAAHGEA WAWRRLCLEF ECRLDGRLLV RERVDQSGEE
     LRALAELAGS GAAACFANAI LIPGAEADED WRAAVEGLHR DGAWVGVSAL REAGWSIKVI
     APDGAYLRET LRAIRAVLAE AFPRMRCDPR RL