ID   URED_PARMW              Reviewed;         311 AA.
AC   Q7U3I6;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=SYNW2446;
OS   Parasynechococcus marenigrum (strain WH8102).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Parasynechococcus; Parasynechococcus marenigrum.
OX   NCBI_TaxID=84588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH8102;
RX   PubMed=12917641; DOI=10.1038/nature01943;
RA   Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P.,
RA   Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T.,
RA   Dufresne A., Partensky F., Webb E.A., Waterbury J.;
RT   "The genome of a motile marine Synechococcus.";
RL   Nature 424:1037-1042(2003).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; BX569695; CAE08961.1; -; Genomic_DNA.
DR   RefSeq; WP_011129299.1; NC_005070.1.
DR   AlphaFoldDB; Q7U3I6; -.
DR   SMR; Q7U3I6; -.
DR   STRING; 84588.SYNW2446; -.
DR   EnsemblBacteria; CAE08961; CAE08961; SYNW2446.
DR   KEGG; syw:SYNW2446; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_4_0_3; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000001422; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..311
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340529"
SQ   SEQUENCE   311 AA;  34111 MW;  7D92594347DC8922 CRC64;
     MQSLEPWHGR CRLQFQTNNG STKHQGGCTA PFKLLRADVG DHGRCELPLL HTAGGLVGGD
     ELSIELDLGP DSRSLITSVA AQKVYGSVGR SRLHPDGAWT QQSVTCRLED TSDLEWLPQE
     LVLYADALFQ QTLTVSLPDN ASFLSAEIVR LGRTAAGEQL NRGRWRSCLE IQRDGAHQPR
     WELVDRLELG DTSLNDPHGL GGAPVFGSLV WAAPMPLTGE QITLLLAGAR HDRDGLEGTM
     RCSSLDQGLI ARYAGHSSRD ARFWFSRIWA RTRALRGLST PRIPRVWPLQ EQPLTGQPFT
     ANASPTAATT H