ID   URED_PHOLL              Reviewed;         321 AA.
AC   Q7N4Y3;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=plu2177;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; BX571866; CAE14470.1; -; Genomic_DNA.
DR   RefSeq; WP_011146431.1; NC_005126.1.
DR   AlphaFoldDB; Q7N4Y3; -.
DR   SMR; Q7N4Y3; -.
DR   STRING; 243265.plu2177; -.
DR   EnsemblBacteria; CAE14470; CAE14470; plu2177.
DR   GeneID; 24166461; -.
DR   KEGG; plu:plu2177; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_0_6; -.
DR   OMA; IPFENAH; -.
DR   OrthoDB; 1764668at2; -.
DR   BioCyc; PLUM243265:PLU_RS10875-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..321
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346585"
SQ   SEQUENCE   321 AA;  35978 MW;  1FD773A27C001958 CRC64;
     MTSTRLPQNI GEACQQANNL GVNAPELARF QDEPPQMASG DVGKSGYLRL GFARRGDRSI
     LAQMKRRVPY LVQRALYWDE ALPQMPCVFM ISTSGCILQG DRLALDIHVA PEAFGHVTTQ
     SATKIHSMEN NYAAQVQTIQ IEQGGYLEMM PDPVIPHSGS RFITDTQITI HPTATLIYSE
     IIMSGRKYHL ADQGFKFDVY SSRITATDFD GKILFTERYV LEPKKQSLNS VGVMGPFHVF
     GNVILLTPQL HHDRILARMA PQYDAETGIA SGTSRLPHQC GLIFKVLGKE TYQVKAGIRL
     FWRIAREEIL GVTLPEPFIW R