ID   URED_POLNA              Reviewed;         276 AA.
AC   A1VKZ3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Pnap_1004;
OS   Polaromonas naphthalenivorans (strain CJ2).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=365044;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CJ2;
RX   PubMed=19453698; DOI=10.1111/j.1462-2920.2009.01947.x;
RA   Yagi J.M., Sims D., Brettin T., Bruce D., Madsen E.L.;
RT   "The genome of Polaromonas naphthalenivorans strain CJ2, isolated from coal
RT   tar-contaminated sediment, reveals physiological and metabolic versatility
RT   and evolution through extensive horizontal gene transfer.";
RL   Environ. Microbiol. 11:2253-2270(2009).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000529; ABM36321.1; -; Genomic_DNA.
DR   RefSeq; WP_011800415.1; NC_008781.1.
DR   AlphaFoldDB; A1VKZ3; -.
DR   SMR; A1VKZ3; -.
DR   STRING; 365044.Pnap_1004; -.
DR   EnsemblBacteria; ABM36321; ABM36321; Pnap_1004.
DR   KEGG; pna:Pnap_1004; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_4; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000000644; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..276
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340471"
SQ   SEQUENCE   276 AA;  30008 MW;  3B3042B1DF4E3838 CRC64;
     MTWNATLALD YTRQAEKTVA HFRHSGPLRI LQSLYPEGDG ICHNVIVHPP GGLVGGDTLD
     LAFTAGAGAH GLVTTPGATR FYRSTGEPAL QRTRLSLEAG ARMEWLPLEA ICYSGCLAEN
     RLTMELASGA ELIGWDVTAF GLPAASLPFA HGHFCQHIEM PGVWLERARI AAGDTLLMDS
     PLGLAGQRCM ASIFFVAGSK LERNRRQQAL DVAREVIEAH ALRATAGATS PDGQVVVVRV
     LAPLVEPAMT LLRQVWQAWR SHFWQQPAAL PRIWSM