URED_PROM9
ID URED_PROM9 Reviewed; 300 AA.
AC Q31B52;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN OrderedLocusNames=PMT9312_0833;
OS Prochlorococcus marinus (strain MIT 9312).
OC Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC Prochlorococcus.
OX NCBI_TaxID=74546;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9312;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Lykidis A., Richardson P.;
RT "Complete sequence of Prochlorococcus marinus str. MIT 9312.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of urease via the functional
CC incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
CC -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC hydrolysis-dependent molecular chaperone, activating the urease
CC apoprotein by helping to assemble the nickel containing metallocenter
CC of UreC. The UreE protein probably delivers the nickel.
CC {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC Rule:MF_01384}.
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DR EMBL; CP000111; ABB49893.1; -; Genomic_DNA.
DR RefSeq; WP_011376388.1; NC_007577.1.
DR AlphaFoldDB; Q31B52; -.
DR SMR; Q31B52; -.
DR STRING; 74546.PMT9312_0833; -.
DR EnsemblBacteria; ABB49893; ABB49893; PMT9312_0833.
DR KEGG; pmi:PMT9312_0833; -.
DR eggNOG; COG0829; Bacteria.
DR HOGENOM; CLU_056339_4_0_3; -.
DR OMA; CQHIIVH; -.
DR OrthoDB; 1764668at2; -.
DR Proteomes; UP000002715; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR HAMAP; MF_01384; UreD; 1.
DR InterPro; IPR002669; UreD.
DR PANTHER; PTHR33643; PTHR33643; 1.
DR Pfam; PF01774; UreD; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel insertion.
FT CHAIN 1..300
FT /note="Urease accessory protein UreD"
FT /id="PRO_0000340478"
SQ SEQUENCE 300 AA; 34068 MW; C58542C7A28C79B6 CRC64;
MIKTSWEGNC FLNFFNNKAS IGNVDKTIFK SKSTSPYKLL KSTHDEEGRC ILPVLHTAGG
LVGGDLLQFE VNLEKNSKVL LTTSSAQKVY GSVGRSKINP KGSFSKQKNY IKILDNSHLE
YLPQETIIFA NGLYDQKFKV FISENSSFLF TDLIRLGRSS SGESIESGVF RSKLEIIRNN
DLYDDWEYVD QIELSKASYE AKSGMDYMPV FGSLIWVCEK DFSKLKINNL VGNIKKFFKE
SDNHLSIGIL ENGISVRFLG SSSQEARKCF FCIWKQIRSV CGFCEPKYQG VWPLQDSMNY