ID   URED_PSEA7              Reviewed;         280 AA.
AC   A6VCX1;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=PSPA7_5585;
OS   Pseudomonas aeruginosa (strain PA7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=381754;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA7;
RA   Dodson R.J., Harkins D., Paulsen I.T.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000744; ABR86377.1; -; Genomic_DNA.
DR   RefSeq; WP_003116109.1; NC_009656.1.
DR   AlphaFoldDB; A6VCX1; -.
DR   SMR; A6VCX1; -.
DR   EnsemblBacteria; ABR86377; ABR86377; PSPA7_5585.
DR   KEGG; pap:PSPA7_5585; -.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000001582; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..280
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340483"
SQ   SEQUENCE   280 AA;  30775 MW;  1811BDD37F7B41DF CRC64;
     MTAALPDLSF HPAWHAQLEL AYARAGDATR PVTRRHAGPL RVQKHLYAEG PEVCQHILVH
     PPGGIAGGDS LAFDVRLGER AWAQLTSPGA AKWYRAACPS RQTLEIHLEP GATLEWLPQE
     SIVFAGAQAE LETRIQLRGD ARLFYWDMVA LGRPASGERF ASGHFVAALD IRRDDRLLWH
     ERQRIDGGDR LLDSPIGLAG HPVLATLVAS GEIDTDLLQR CRALPCAGRG NLSQLPGGLL
     VARCLADEAL HARAWLIELW RLLRPALLGR EAVPPRIWST