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URED_PSEE4
ID   URED_PSEE4              Reviewed;         277 AA.
AC   Q1IBP3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=PSEEN2093;
OS   Pseudomonas entomophila (strain L48).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=384676;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L48;
RX   PubMed=16699499; DOI=10.1038/nbt1212;
RA   Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C.,
RA   Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P.,
RA   Weissenbach J., Lemaitre B., Medigue C., Boccard F.;
RT   "Complete genome sequence of the entomopathogenic and metabolically
RT   versatile soil bacterium Pseudomonas entomophila.";
RL   Nat. Biotechnol. 24:673-679(2006).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CT573326; CAK14922.1; -; Genomic_DNA.
DR   RefSeq; WP_011533325.1; NC_008027.1.
DR   AlphaFoldDB; Q1IBP3; -.
DR   SMR; Q1IBP3; -.
DR   STRING; 384676.PSEEN2093; -.
DR   EnsemblBacteria; CAK14922; CAK14922; PSEEN2093.
DR   KEGG; pen:PSEEN2093; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000000658; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..277
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340485"
SQ   SEQUENCE   277 AA;  30400 MW;  C80382EA04D96B6D CRC64;
     MSLAQQIEPP QADPGWSAHL QLRFIQREGV TRLGARRHVG PLLVQRPFYP EGAPCHVYVL
     HPPGGIVAGD RLELDIHLEA GSHALLTMPG ASKFYRSIGP TAHLAQRFHL AAGSTLEWLP
     QDSIFFNGAQ ASLDSRFSVE PGARLLAWET LCLGRPVMGE RFDQGAIDSR LCIDLPGEPG
     LHERLRIEGG RLDKVGGHPL VATFCATPAD QAVLEQVRQQ LEALDTPAGA TLLGPLLVIR
     LLDHDNQHLQ RNLQRLWHLL RPAVLGLAPC PPRIWAT
 
 
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