ID   URED_PSEF5              Reviewed;         279 AA.
AC   Q4KJ05;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=PFL_0636;
OS   Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=220664;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5;
RX   PubMed=15980861; DOI=10.1038/nbt1110;
RA   Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.A.,
RA   Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA   Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA   Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA   Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S. III,
RA   Thomashow L.S., Loper J.E.;
RT   "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT   Pf-5.";
RL   Nat. Biotechnol. 23:873-878(2005).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000076; AAY96043.1; -; Genomic_DNA.
DR   RefSeq; WP_011059004.1; NC_004129.6.
DR   AlphaFoldDB; Q4KJ05; -.
DR   SMR; Q4KJ05; -.
DR   STRING; 220664.PFL_0636; -.
DR   PRIDE; Q4KJ05; -.
DR   EnsemblBacteria; AAY96043; AAY96043; PFL_0636.
DR   KEGG; pfl:PFL_0636; -.
DR   PATRIC; fig|220664.5.peg.652; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000008540; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..279
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340486"
SQ   SEQUENCE   279 AA;  30644 MW;  62B4B796001881D0 CRC64;
     MNLPAATALF TPSWHAELEL AYARCGATTR PVLRRHLGPL RVQKHLYAEG PEVCQHIIVH
     PPGGIAGGDR LAISARVDSG AWAQLTSPGA AKWYRATGPA SQTLNLQVAP GATLEWLPQE
     TIVFSAAQAE LTTRIELQGD ARLFYWDIIA LGRPASGERF EQGHFQAHLD LYRDGRPLWH
     ERQRIGGGDG LLDSPIGLDG QPVFATLLVT GEIDSELLER CRALAHPVRG DLSQLPGLLV
     ARCLASEALQ ARAWLIELWR LLRPALLGRE ARPPRIWNT