ID   URED_PSEMY              Reviewed;         278 AA.
AC   A4XQ48;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Pmen_0696;
OS   Pseudomonas mendocina (strain ymp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=399739;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ymp;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Hersman L., Dubois J., Maurice P., Richardson P.;
RT   "Complete sequence of Pseudomonas mendocina ymp.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000680; ABP83464.1; -; Genomic_DNA.
DR   RefSeq; WP_011920878.1; NC_009439.1.
DR   AlphaFoldDB; A4XQ48; -.
DR   SMR; A4XQ48; -.
DR   STRING; 399739.Pmen_0696; -.
DR   EnsemblBacteria; ABP83464; ABP83464; Pmen_0696.
DR   KEGG; pmy:Pmen_0696; -.
DR   PATRIC; fig|399739.8.peg.704; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..278
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340488"
SQ   SEQUENCE   278 AA;  30681 MW;  A35AB74EA1CF44B8 CRC64;
     MNLPAALFTP SWPAELELAY ARHGERTTPV RRRHLGPLRV QKHLHAEGPE VCQHIIVHPP
     GGIAGGDRLD ISAHAGERTW VQLTSPGAAK WYRAAGVARQ DLRLRVEAGA TLEWLPQETI
     VYAGAQAELH TQIELHGDAR LFYWDIVALG RPAADERFAS GHFQAALDVR RDGRLLWHER
     QRVSGGDGLL DSPIGLNGQP VFATLLVSGE VDNELLERCR EVNIDGVRGD LSQLAGLLVA
     RCLASEALKA RAWLIALWRL LRPALLGREA VPPRIWST