ID   URED_RALSO              Reviewed;         295 AA.
AC   Q8XXS7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=RSc2036;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AL646052; CAD15738.1; -; Genomic_DNA.
DR   RefSeq; WP_011001971.1; NC_003295.1.
DR   AlphaFoldDB; Q8XXS7; -.
DR   SMR; Q8XXS7; -.
DR   STRING; 267608.RSc2036; -.
DR   EnsemblBacteria; CAD15738; CAD15738; RSc2036.
DR   GeneID; 60501548; -.
DR   KEGG; rso:RSc2036; -.
DR   PATRIC; fig|267608.8.peg.2068; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_4; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340500"
SQ   SEQUENCE   295 AA;  31826 MW;  1D14A707CFD36E92 CRC64;
     MRHPDFPVPP RIDAFASWEA SLRLAFARRG GRTVLASCRH RGPLRVQKAL YPEGEGVCHV
     VLLHPPAGIA GGDVLDIGIE LGAEAHAVLT TPGATKWYKS PGRTAMQQVA IRLDAGARLD
     WLPQENIVFN QARPVIDLTL DLAPGAAAIG WDITMLGRHA AGESWQEGRI AMHTRLRCEG
     QPLWIESTAF DAQSPVLGAT TGMAGFHVVG TLWAVGAGAT EALAETLAEQ LPYRDDLRAG
     VTCLTQDAPG RPSVLLLRVL ARRPEDARAL LSQTWLALRE PIHGVAGRPL RLWAT