ID   URED_RHILV              Reviewed;         273 AA.
AC   Q8RPY8;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
OS   Rhizobium leguminosarum bv. viciae.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=387;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UPM791;
RX   PubMed=11889482; DOI=10.1007/s00203-001-0392-0;
RA   Toffanin A., Cadahia E., Imperial J., Ruiz-Argueso T., Palacios M.;
RT   "Characterization of the urease gene cluster from Rhizobium leguminosarum
RT   bv. viciae.";
RL   Arch. Microbiol. 177:290-298(2002).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AF347070; AAL83824.1; -; Genomic_DNA.
DR   RefSeq; WP_018517017.1; NZ_WIEG01000008.1.
DR   AlphaFoldDB; Q8RPY8; -.
DR   SMR; Q8RPY8; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..273
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340502"
SQ   SEQUENCE   273 AA;  29317 MW;  3D8CE83F9EA68E88 CRC64;
     MTTVAASTRP QRAEGRGHLA AKLFDGRTRI RELYQEGAAK IRLPDTFDAS MEAVIINTAG
     GLTGGDRMDW SVDAGAGTRI DVTTQACEKI YKASAGTAEV TTSIEVGAQA RVDWLPQETI
     LFDRAALSRR LDVDLDEDSE FLAVEAVLLG RKAMGETVET GLFRDRWRIR RSGRLIHAEE
     LRLSDGVAAL AARQAVLGGQ VAFATLLYAG PLSEAYLGKV RPLVEGSMGG ASAWDGKLVV
     RLAAADGFSL RKILIPVISA LRNGAPVPKV WNL