ID   URED_RHOP2              Reviewed;         279 AA.
AC   Q2IZ53;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=RPB_1799;
OS   Rhodopseudomonas palustris (strain HaA2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HaA2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A.,
RA   Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris HaA2.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000250; ABD06507.1; -; Genomic_DNA.
DR   RefSeq; WP_011440695.1; NC_007778.1.
DR   AlphaFoldDB; Q2IZ53; -.
DR   SMR; Q2IZ53; -.
DR   STRING; 316058.RPB_1799; -.
DR   EnsemblBacteria; ABD06507; ABD06507; RPB_1799.
DR   KEGG; rpb:RPB_1799; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   OMA; MARFCAQ; -.
DR   Proteomes; UP000008809; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..279
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340513"
SQ   SEQUENCE   279 AA;  29313 MW;  79F20566333738D1 CRC64;
     MIQAETSAAD SAVFAGNRAQ GAVRFDVRAV DGVTRRGQLH ESGSLRVRFP SPEQQGLSAV
     LVNTAGGIAG GDRFGVDIAV GESARLTLTT AAAEKIYRSH GPAAQLDIAL QVAEGGHLAW
     LPQETILFDQ ARVERRIDID LAAGASLLLC ESVIFGRSAM GETMRSGRFT DRWRLRIGGK
     LVFAETVRLD GDIGALLGRP AVAKGGVAIG TALIAPGDAA LVARLREDAD GFGAEVGITA
     WNGIAMARFC AQDAAKLRAD MMAVLRRAAG RALPRLWLG