ID   URED_SHEHH              Reviewed;         305 AA.
AC   B0TT68;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Shal_3464;
OS   Shewanella halifaxensis (strain HAW-EB4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=458817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB4;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA   Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella halifaxensis HAW-EB4.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000931; ABZ78009.1; -; Genomic_DNA.
DR   RefSeq; WP_012278529.1; NC_010334.1.
DR   AlphaFoldDB; B0TT68; -.
DR   SMR; B0TT68; -.
DR   STRING; 458817.Shal_3464; -.
DR   EnsemblBacteria; ABZ78009; ABZ78009; Shal_3464.
DR   KEGG; shl:Shal_3464; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_6; -.
DR   OMA; CQHIIVH; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000001317; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..305
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346593"
SQ   SEQUENCE   305 AA;  34161 MW;  515535B1D7E9881C CRC64;
     MNIPESVSYK RPESHFGWRA ELSLKYGIKR EKTRLLERHQ LGPLTVQKTF YPEGAACHTY
     LLHPPGGVVG GDQLSFNIDV GTQAHALLTT PGATKFYRSN GEQAWQSQEL TVAKDGLLEW
     LPMENIFFPG ANCKLLTQVN LATNARFIGW EMQCFGRPML AETFDNGQVL GQTFIHRDHR
     VLLAETLRVK SQSHIDQAAA LRNFAMSGSL YITPIEPELI DKINQVIDEQ QLRFGSEILL
     GSSEIGSAST SSAMSLTSTA EDSLIVVRAL GQQTEPMMAS FVQIWRCVRL HWFGELPEVP
     RIWST