ID   URED_SYNP2              Reviewed;         285 AA.
AC   B1XIC0;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   OrderedLocusNames=SYNPCC7002_A2123;
OS   Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum
OS   quadruplicatum).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RA   Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T.,
RA   Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J.,
RA   Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.;
RT   "Complete sequence of Synechococcus sp. PCC 7002.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000951; ACB00105.1; -; Genomic_DNA.
DR   RefSeq; WP_012307725.1; NC_010475.1.
DR   AlphaFoldDB; B1XIC0; -.
DR   SMR; B1XIC0; -.
DR   STRING; 32049.SYNPCC7002_A2123; -.
DR   EnsemblBacteria; ACB00105; ACB00105; SYNPCC7002_A2123.
DR   KEGG; syp:SYNPCC7002_A2123; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_3; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000001688; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..285
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346610"
SQ   SEQUENCE   285 AA;  32352 MW;  897F95B26A1FCD0F CRC64;
     MQDQQQVIHK AQPWHGKVGL IYGQRQGKTE MQRCFTQAPF RIQRPFYPEG NRVCHTVLLH
     TAGGIVGGDR LSLDLELKPE SHVFLTTAAA NKIYRTNGET AQQDGIIHQA PGSILEYFPQ
     EMIIFDGAEY HQSLRVNLAP GAVWCGWEVL RFGRTARGEK FISGNWRGLT EIWQDDELLW
     GDRQWLPGHP EVFAAWNGLN NQPVVGSLAL VGLEISEAQM AELRQTMATI QQGLGGITQL
     PKGVLCRYRG PSSTEVKRWF ISLWQNWRSL YSPQPPTLSR VWQTY