ID   URED_SYNS9              Reviewed;         311 AA.
AC   Q3AVR4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   OrderedLocusNames=Syncc9902_2254;
OS   Synechococcus sp. (strain CC9902).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9902;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9902.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABB27212.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000097; ABB27212.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041425232.1; NC_007513.1.
DR   AlphaFoldDB; Q3AVR4; -.
DR   SMR; Q3AVR4; -.
DR   STRING; 316279.Syncc9902_2254; -.
DR   EnsemblBacteria; ABB27212; ABB27212; Syncc9902_2254.
DR   KEGG; sye:Syncc9902_2254; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_4_0_3; -.
DR   OrthoDB; 1764668at2; -.
DR   Proteomes; UP000002712; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion; Reference proteome.
FT   CHAIN           1..311
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340525"
SQ   SEQUENCE   311 AA;  34328 MW;  25502031283FD8E8 CRC64;
     MQRLNPWHGT CRLQFSADAD TTHHQGGCTA PFKLMRAERG NDGRCELPLL HSAGGLVGGD
     QLSVDLELGR NSRALITSVA AQKVYGSIGR SRLHPKGTWA NQSVSCRLGS NSDLEWLPQE
     LVVYADALVE QSLDVQLADD ASFLSAEIVR LGRTAAGEDL GQGCWRSAVS LRRIGENGTR
     WEQVDRLELS GDALHHRHGL NGDAVFGTLI WAAPAPLTNP TLKSLLTNAR NDRAGLEGQM
     QCSRLEQGLI ARYVGPSSRD ARFWFSRIWA RTRAQRQLSE PRIPRVWPLQ EQPLRQQVFI
     ENIASSNAAT H