ID   URED_SYNSC              Reviewed;         311 AA.
AC   Q3AGD3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   OrderedLocusNames=Syncc9605_2624;
OS   Synechococcus sp. (strain CC9605).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=110662;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9605;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9605.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABB36349.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000110; ABB36349.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041435898.1; NC_007516.1.
DR   AlphaFoldDB; Q3AGD3; -.
DR   SMR; Q3AGD3; -.
DR   STRING; 110662.Syncc9605_2624; -.
DR   EnsemblBacteria; ABB36349; ABB36349; Syncc9605_2624.
DR   KEGG; syd:Syncc9605_2624; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_4_0_3; -.
DR   OrthoDB; 1764668at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..311
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340524"
SQ   SEQUENCE   311 AA;  33982 MW;  AE2782ED4A09CD56 CRC64;
     MQRLDPWHGR CDLQFHATNG STKHQGGCTA PFKLLRSERG EDGRCELPVL HTAGGLVGGD
     QLSLDFKLEA NSRGLITSVA AQKVYGSIGR SRLQPEGCFA HQQVRCSLAS GSDLEWLPQE
     LVLYADALFE QQLTVTLPQD ASFLSAEIVR LGRTAAGETL QQGRWRSSLT IQRLAGESST
     WELADRVELG GASLESPHGL GGAPVFGTLV WAAPMAMGAE TTASVLEGAR ADREGLTGTM
     RCGALNQGLI ARYSGESSRD ARFWFSRIWE RTRTIRGLTR PRIPRVWPLQ EQPLRRQTST
     VNAFEAAAET H