ID   URED_TRIEI              Reviewed;         279 AA.
AC   Q117Z6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Tery_0749;
OS   Trichodesmium erythraeum (strain IMS101).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
OC   Microcoleaceae; Trichodesmium.
OX   NCBI_TaxID=203124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMS101;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Richardson P.;
RT   "Complete sequence of Trichodesmium erythraeum IMS101.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000393; ABG50178.1; -; Genomic_DNA.
DR   RefSeq; WP_011610571.1; NC_008312.1.
DR   AlphaFoldDB; Q117Z6; -.
DR   SMR; Q117Z6; -.
DR   STRING; 203124.Tery_0749; -.
DR   EnsemblBacteria; ABG50178; ABG50178; Tery_0749.
DR   KEGG; ter:Tery_0749; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_1_3; -.
DR   OMA; IPFENAH; -.
DR   OrthoDB; 1764668at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..279
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346612"
SQ   SEQUENCE   279 AA;  31272 MW;  FC095A6C336BD824 CRC64;
     MSTNNLDIKL NCNSSGQTIV THQYTTHPLR LSGVFRLDTT DPRTAYLYLI NTSPGLLAGD
     NLSLSLQLEK GTSVYLTDQA AIKVHAMPMT TTKANTNIKI KVEAGARLEL VAEPIILFAD
     AALEQTTYIQ LHSRAELFWS EIILPGRLAR GEWYEFRYYL SQLEITSMTE EICFRDAIHL
     EGKQNIFKHR DLFAAKPVLA NLIVVQPHSD LEVLSQKLEN LEAANCPDLL LGSSILPNNK
     GLLLRALASK TPQIKKYIKY ALNCVRNLTN RSSLPYISK