ID   URED_TRIV2              Reviewed;         279 AA.
AC   Q3M708;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Ava_3622;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000117; ABA23228.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3M708; -.
DR   SMR; Q3M708; -.
DR   STRING; 240292.Ava_3622; -.
DR   EnsemblBacteria; ABA23228; ABA23228; Ava_3622.
DR   KEGG; ava:Ava_3622; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_0_0_3; -.
DR   OMA; CQHIIVH; -.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..279
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340407"
SQ   SEQUENCE   279 AA;  31409 MW;  C783B12D59338042 CRC64;
     MAFNSQPIEG WHGKLDLVYA DRSNSTQLIY NHQQAPLKVQ RPFYPEGEKV CHSVILHTAG
     GVVGGDRLSY NLHLQPNAQA LITTAAAGKI YRSEGLQARQ TIDIKIDAGA CLEWLPQETI
     LFNGAIYRQD LRVELATGAN FLGWEITRFG RSARGEKFYQ GEWRSHTEIW RQGVPLWIDR
     QWLPGNEAVF HSPHGLAGQP IVGSLVWLGS AVSTEIIAKA RNLGNTQGEK GVTSLENGFL
     CRYRGASTSE VRNWFTDVWQ LLRVEFFSRS KCTPRVWQT