ID   URED_XANP2              Reviewed;         289 AA.
AC   A7IMY3;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=Xaut_4154;
OS   Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Xanthobacteraceae; Xanthobacter.
OX   NCBI_TaxID=78245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1158 / Py2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA   Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Tapia R., Brainard J., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.;
RT   "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; CP000781; ABS69376.1; -; Genomic_DNA.
DR   RefSeq; WP_012116122.1; NC_009720.1.
DR   AlphaFoldDB; A7IMY3; -.
DR   SMR; A7IMY3; -.
DR   STRING; 78245.Xaut_4154; -.
DR   EnsemblBacteria; ABS69376; ABS69376; Xaut_4154.
DR   KEGG; xau:Xaut_4154; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_2_0_5; -.
DR   OMA; MARFCAQ; -.
DR   OrthoDB; 1764668at2; -.
DR   PhylomeDB; A7IMY3; -.
DR   Proteomes; UP000002417; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Reference proteome.
FT   CHAIN           1..289
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000346613"
SQ   SEQUENCE   289 AA;  30774 MW;  68FC942ACACCFE96 CRC64;
     MTTSAASWRS DPADPSVASA RERALRQRSE GRVRITASAF GGVTRLTDLA EGGALRARLP
     RGGPGLEAVI VNTAGGVACG DVFSIEAKAG PGAHLTVATP AAEKVYRSDG LCADIQVRLV
     AEAGARLDWL PQETILFDRA RLRRRYEIDL SATASFLSFE ALMLGRLAHG DAMGEGHLED
     HWRLRRDGAL IFADALRLAG PMGALLARPA VAGGNRALAT LLYVAPDAEA RLEEARALLD
     AARCEAGASA WNGLLCVRLL APDIETLRRD ATSFLMAFRN APLPRVWAT