ID   URED_YERE8              Reviewed;         327 AA.
AC   A1JKE3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Urease accessory protein UreD {ECO:0000255|HAMAP-Rule:MF_01384};
GN   Name=ureD {ECO:0000255|HAMAP-Rule:MF_01384}; OrderedLocusNames=YE0957;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Required for maturation of urease via the functional
CC       incorporation of the urease nickel metallocenter. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
CC   -!- SUBUNIT: UreD, UreF and UreG form a complex that acts as a GTP-
CC       hydrolysis-dependent molecular chaperone, activating the urease
CC       apoprotein by helping to assemble the nickel containing metallocenter
CC       of UreC. The UreE protein probably delivers the nickel.
CC       {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01384}.
CC   -!- SIMILARITY: Belongs to the UreD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01384}.
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DR   EMBL; AM286415; CAL11055.1; -; Genomic_DNA.
DR   RefSeq; WP_011815718.1; NC_008800.1.
DR   RefSeq; YP_001005291.1; NC_008800.1.
DR   AlphaFoldDB; A1JKE3; -.
DR   SMR; A1JKE3; -.
DR   STRING; 393305.YE0957; -.
DR   EnsemblBacteria; CAL11055; CAL11055; YE0957.
DR   KEGG; yen:YE0957; -.
DR   PATRIC; fig|393305.7.peg.1058; -.
DR   eggNOG; COG0829; Bacteria.
DR   HOGENOM; CLU_056339_1_0_6; -.
DR   OMA; IPFENAH; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   HAMAP; MF_01384; UreD; 1.
DR   InterPro; IPR002669; UreD.
DR   PANTHER; PTHR33643; PTHR33643; 1.
DR   Pfam; PF01774; UreD; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel insertion.
FT   CHAIN           1..327
FT                   /note="Urease accessory protein UreD"
FT                   /id="PRO_0000340533"
SQ   SEQUENCE   327 AA;  36486 MW;  BEA3413DD61E86A2 CRC64;
     MTSQSQNIVE TPSRVRAHAL GINAPELAQY QDEPAQMRSG AVGKSGYLKL RFAKREHRSI
     LAEMERRVPS MVQKALYWDE EMPELPCVTM ISTSGCILQG DRLATDVIVE AGACAHVTTQ
     SATKVHMMNA NYASQIQNFT VEEGGYLEFM PDPLIPHRNS RFITDTTINI HPTATAIYSE
     VLMSGRKYHH ADERFGFDVY SSRVAAHVFL GKEQPAGKEL FVEKYVLEPK SESLDAIGVM
     QSFDAFGNVI LLTPKQHHER ILARVPAHFD IKGGIASGAT RLPNDCGLVF KALGIDSAGV
     KNEIRQFWKI AREEILGVTL PEKFLWR