ID   UREE_ACTPL              Reviewed;         187 AA.
AC   O54422;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN   Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822};
OS   Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=715;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CM5 / Serotype 1;
RX   PubMed=9353010; DOI=10.1128/iai.65.11.4389-4394.1997;
RA   Bosse J.T., Macinnes J.I.;
RT   "Genetic and biochemical analyses of Actinobacillus pleuropneumoniae
RT   urease.";
RL   Infect. Immun. 65:4389-4394(1997).
CC   -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC       Probably functions as a nickel donor during metallocenter assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00822}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC00062.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U89957; AAC00062.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_042655078.1; NZ_LS483358.1.
DR   AlphaFoldDB; O54422; -.
DR   SMR; O54422; -.
DR   STRING; 228399.appser1_17350; -.
DR   GeneID; 66258368; -.
DR   PATRIC; fig|416269.6.peg.1680; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR   CDD; cd00571; UreE; 1.
DR   HAMAP; MF_00822; UreE; 1.
DR   InterPro; IPR012406; UreE.
DR   InterPro; IPR007864; UreE_C_dom.
DR   InterPro; IPR004029; UreE_N.
DR   InterPro; IPR036118; UreE_N_sf.
DR   Pfam; PF05194; UreE_C; 1.
DR   Pfam; PF02814; UreE_N; 1.
DR   PIRSF; PIRSF036402; Ureas_acces_UreE; 1.
DR   SMART; SM00988; UreE_N; 1.
DR   SUPFAM; SSF69287; SSF69287; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Nickel insertion.
FT   CHAIN           1..187
FT                   /note="Urease accessory protein UreE"
FT                   /id="PRO_0000067627"
FT   REGION          154..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..187
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   187 AA;  21140 MW;  9F3CD3715275E972 CRC64;
     MQILNPILPV MEDILGNLAE LKASGKITNQ QIDTVELQWY ESERNILRKT SKSGREVAFR
     LLKEGQRLKH DDVVFVSESL VIAIEILPSE VIVLSPKTLP EMARACYEIG NKHSPLFLDG
     DEVTLPYDKP MFEWLQAAGF GPQKAERRLS QALRANSAQG HGHSHGHSHS HDHHGYHHHG
     DGNWHKH