UREE_CORGL
ID UREE_CORGL Reviewed; 157 AA.
AC Q9RHM3; Q9L419;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 02-AUG-2002, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822};
GN OrderedLocusNames=Cgl0087, cg0116;
OS Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS JCM 1318 / LMG 3730 / NCIMB 10025).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=196627;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC STRAIN=ATCC 13869 / DSMZ 1412 / NCIMB 9567;
RX PubMed=11328647; DOI=10.3109/10425170009033989;
RA Puskas L.G., Inui M., Yukawa H.;
RT "Structure of the urease operon of Corynebacterium glutamicum.";
RL DNA Seq. 11:383-394(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND OPERON STRUCTURE.
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=10930756; DOI=10.1111/j.1574-6968.2000.tb09248.x;
RA Nolden L., Beckers G., Moeckel B., Pfefferle W., Nampoothiri K.M.,
RA Kraemer R., Burkovski A.;
RT "Urease of Corynebacterium glutamicum: organization of corresponding genes
RT and investigation of activity.";
RL FEMS Microbiol. Lett. 189:305-310(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA Ikeda M., Nakagawa S.;
RT "The Corynebacterium glutamicum genome: features and impacts on
RT biotechnological processes.";
RL Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT impact on the production of L-aspartate-derived amino acids and vitamins.";
RL J. Biotechnol. 104:5-25(2003).
CC -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC Probably functions as a nickel donor during metallocenter assembly.
CC {ECO:0000255|HAMAP-Rule:MF_00822}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC -!- INDUCTION: By urea and nitrogen starvation.
CC {ECO:0000269|PubMed:11328647}.
CC -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC Rule:MF_00822}.
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DR EMBL; AB029154; BAA88555.1; -; Genomic_DNA.
DR EMBL; AJ251883; CAB81938.1; -; Genomic_DNA.
DR EMBL; BA000036; BAB97480.1; -; Genomic_DNA.
DR EMBL; BX927148; CAF18655.1; -; Genomic_DNA.
DR RefSeq; NP_599339.1; NC_003450.3.
DR RefSeq; WP_011013379.1; NC_006958.1.
DR AlphaFoldDB; Q9RHM3; -.
DR SMR; Q9RHM3; -.
DR STRING; 196627.cg0116; -.
DR KEGG; cgb:cg0116; -.
DR KEGG; cgl:Cgl0087; -.
DR PATRIC; fig|196627.13.peg.88; -.
DR eggNOG; COG2371; Bacteria.
DR HOGENOM; CLU_093757_3_1_11; -.
DR OMA; YVDLEWF; -.
DR Proteomes; UP000000582; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR CDD; cd00571; UreE; 1.
DR HAMAP; MF_00822; UreE; 1.
DR InterPro; IPR012406; UreE.
DR InterPro; IPR007864; UreE_C_dom.
DR InterPro; IPR004029; UreE_N.
DR InterPro; IPR036118; UreE_N_sf.
DR Pfam; PF05194; UreE_C; 1.
DR Pfam; PF02814; UreE_N; 1.
DR PIRSF; PIRSF036402; Ureas_acces_UreE; 1.
DR SMART; SM00988; UreE_N; 1.
DR SUPFAM; SSF69287; SSF69287; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Cytoplasm; Nickel; Nickel insertion; Reference proteome.
FT CHAIN 1..157
FT /note="Urease accessory protein UreE"
FT /id="PRO_0000067631"
FT CONFLICT 42
FT /note="P -> S (in Ref. 1; BAA88555)"
FT /evidence="ECO:0000305"
FT CONFLICT 52..57
FT /note="NHGHPI -> ITGTPS (in Ref. 1; BAA88555)"
FT /evidence="ECO:0000305"
FT CONFLICT 69
FT /note="K -> R (in Ref. 1; BAA88555)"
FT /evidence="ECO:0000305"
FT CONFLICT 133..157
FT /note="DEHGIEYQRTELVPPIPFRHSGHTH -> G (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 157 AA; 17644 MW; 4BBAA3381FCD5C21 CRC64;
MIITAIDTNI YDQPEFVEGR DVIGVRFEDL VLDKRIQRVA LPGGEELGLR LNHGHPILRE
GDVLKADDKT VFVVEIIPTD VLVITPSDIH QMGFVAHSLG NRHLPAQFSK PGELTEKAAM
IVQYDHTVVS FLDEHGIEYQ RTELVPPIPF RHSGHTH
