ID   UREE_NATPD              Reviewed;         214 AA.
AC   Q3IRZ1;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN   Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822}; OrderedLocusNames=NP_2018A;
OS   Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS   8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Natronomonas.
OX   NCBI_TaxID=348780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB
RC   2260 / Gabara;
RX   PubMed=16169924; DOI=10.1101/gr.3952905;
RA   Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA   Oesterhelt D.;
RT   "Living with two extremes: conclusions from the genome sequence of
RT   Natronomonas pharaonis.";
RL   Genome Res. 15:1336-1343(2005).
CC   -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC       Probably functions as a nickel donor during metallocenter assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00822}.
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DR   EMBL; CR936257; CAI49100.1; -; Genomic_DNA.
DR   RefSeq; WP_011322729.1; NC_007426.1.
DR   AlphaFoldDB; Q3IRZ1; -.
DR   STRING; 348780.NP_2018A; -.
DR   EnsemblBacteria; CAI49100; CAI49100; NP_2018A.
DR   GeneID; 3703452; -.
DR   KEGG; nph:NP_2018A; -.
DR   eggNOG; arCOG06188; Archaea.
DR   HOGENOM; CLU_095954_0_0_2; -.
DR   OMA; HAIGNQH; -.
DR   OrthoDB; 110334at2157; -.
DR   Proteomes; UP000002698; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   HAMAP; MF_00822; UreE; 1.
DR   InterPro; IPR012406; UreE.
DR   InterPro; IPR004029; UreE_N.
DR   InterPro; IPR036118; UreE_N_sf.
DR   Pfam; PF02814; UreE_N; 1.
DR   SMART; SM00988; UreE_N; 1.
DR   SUPFAM; SSF69287; SSF69287; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Nickel insertion; Reference proteome.
FT   CHAIN           1..214
FT                   /note="Urease accessory protein UreE"
FT                   /id="PRO_0000223462"
FT   REGION          163..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        167..214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   214 AA;  23560 MW;  3B6577E2CCA6AA4A CRC64;
     MRHVDGVVGN RYDDPDLDEQ LHAHEDAGRL ERVVLEAGQR KRSRLRVETD AGTDLGIVVD
     QPELRAGDVL FLDDDAAAVV EFESRTAFVV DLPSPGPETV AAAVELGHRV GNQHWDIAIE
     GGTVYVPVEA DRRIIEDVLG EHIPDSGTTR YASVDASLFI GENAEPSGVD HSHEATDSGH
     GYGEDHDHDH SHDHNHDHDH NHDHDHSHSH DSHE