UREE_UREPA
ID UREE_UREPA Reviewed; 149 AA.
AC Q56559; Q7BSC4; Q7BSC8; Q7BSD3; Q9PQ57;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 2.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822}; OrderedLocusNames=UU431;
OS Ureaplasma parvum serovar 3 (strain ATCC 700970).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX NCBI_TaxID=273119;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 27813 / 7 / Serovar 1;
RX PubMed=8550495; DOI=10.1128/jb.178.3.647-655.1996;
RA Neyrolles O., Ferris S., Behbahani N., Montagnier L., Blanchard A.;
RT "Organization of Ureaplasma urealyticum urease gene cluster and expression
RT in a suppressor strain of Escherichia coli.";
RL J. Bacteriol. 178:647-655(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700970;
RX PubMed=11048724; DOI=10.1038/35037619;
RA Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y.,
RA Cassell G.H.;
RT "The complete sequence of the mucosal pathogen Ureaplasma urealyticum.";
RL Nature 407:757-762(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 27813 / 7 / Serovar 1, ATCC 27818 / Pi / Serovar 6, and
RC ATCC 33697 / U26 / Serovar 14;
RX PubMed=15388749; DOI=10.1099/ijs.0.63073-0;
RA Kong F., Gilbert G.L.;
RT "Postgenomic taxonomy of human ureaplasmas - a case study based on multiple
RT gene sequences.";
RL Int. J. Syst. Evol. Microbiol. 54:1815-1821(2004).
CC -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC Probably functions as a nickel donor during metallocenter assembly.
CC {ECO:0000255|HAMAP-Rule:MF_00822}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC Rule:MF_00822}.
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DR EMBL; L40489; AAA89190.2; -; Genomic_DNA.
DR EMBL; AF222894; AAF30843.1; -; Genomic_DNA.
DR EMBL; AF085730; AAG10353.1; -; Genomic_DNA.
DR EMBL; AF085731; AAG10358.1; -; Genomic_DNA.
DR EMBL; AF085733; AAG10363.1; -; Genomic_DNA.
DR PIR; F82890; F82890.
DR RefSeq; WP_006688775.1; NC_002162.1.
DR AlphaFoldDB; Q56559; -.
DR SMR; Q56559; -.
DR STRING; 273119.UU431; -.
DR EnsemblBacteria; AAF30843; AAF30843; UU431.
DR GeneID; 29672354; -.
DR KEGG; uur:UU431; -.
DR eggNOG; COG2371; Bacteria.
DR HOGENOM; CLU_093757_3_1_14; -.
DR OMA; YVDLEWF; -.
DR Proteomes; UP000000423; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR CDD; cd00571; UreE; 1.
DR HAMAP; MF_00822; UreE; 1.
DR InterPro; IPR012406; UreE.
DR InterPro; IPR007864; UreE_C_dom.
DR InterPro; IPR004029; UreE_N.
DR InterPro; IPR036118; UreE_N_sf.
DR Pfam; PF05194; UreE_C; 1.
DR Pfam; PF02814; UreE_N; 1.
DR PIRSF; PIRSF036402; Ureas_acces_UreE; 1.
DR SMART; SM00988; UreE_N; 1.
DR SUPFAM; SSF69287; SSF69287; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Nickel; Nickel insertion; Reference proteome.
FT CHAIN 1..149
FT /note="Urease accessory protein UreE"
FT /id="PRO_0000067639"
FT CONFLICT 9..11
FT /note="DNI -> APL (in Ref. 1; AAA89190)"
FT /evidence="ECO:0000305"
FT CONFLICT 91..95
FT /note="MAKIA -> WQNC (in Ref. 1; AAA89190)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 149 AA; 17374 MW; 05328FEA0A924AA8 CRC64;
MTVFKEILDN IANIKNVESY QIENIHLTSD DVLKRVIIIS SDQNVEYGIR LEEDKKLMDG
DILYKDDYKL VVIRLELSDV LIITAHTIGE MAKIAHNLGN RHMPAQFTET QMIVPYDYLV
EEYLQDNKAL YERKKIKLKE AFKHCSDAK