ID   UREE_VIBPH              Reviewed;         159 AA.
AC   Q9FAS4;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Urease accessory protein UreE {ECO:0000255|HAMAP-Rule:MF_00822};
GN   Name=ureE {ECO:0000255|HAMAP-Rule:MF_00822};
OS   Vibrio parahaemolyticus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=670;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=TH3996;
RX   PubMed=10992480; DOI=10.1128/iai.68.10.5742-5748.2000;
RA   Park K.-S., Iida T., Yamaichi Y., Oyagi T., Yamamoto K., Honda T.;
RT   "Genetic characterization of DNA region containing the trh and ure genes of
RT   Vibrio parahaemolyticus.";
RL   Infect. Immun. 68:5742-5748(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=TH3996;
RX   PubMed=19075025; DOI=10.1128/iai.01184-08;
RA   Okada N., Iida T., Park K.-S., Goto N., Yasunaga T., Hiyoshi H.,
RA   Matsuda S., Kodama T., Honda T.;
RT   "Identification and characterization of a novel type III secretion system
RT   in trh-positive Vibrio parahaemolyticus strain TH3996 reveal genetic
RT   lineage and diversity of pathogenic machinery beyond the species level.";
RL   Infect. Immun. 77:904-913(2009).
CC   -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel.
CC       Probably functions as a nickel donor during metallocenter assembly.
CC       {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00822}.
CC   -!- SIMILARITY: Belongs to the UreE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00822}.
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DR   EMBL; AB455531; BAB13789.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9FAS4; -.
DR   SMR; Q9FAS4; -.
DR   PRIDE; Q9FAS4; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   GO; GO:0019627; P:urea metabolic process; IEA:InterPro.
DR   CDD; cd00571; UreE; 1.
DR   HAMAP; MF_00822; UreE; 1.
DR   InterPro; IPR012406; UreE.
DR   InterPro; IPR007864; UreE_C_dom.
DR   InterPro; IPR004029; UreE_N.
DR   InterPro; IPR036118; UreE_N_sf.
DR   Pfam; PF05194; UreE_C; 1.
DR   Pfam; PF02814; UreE_N; 1.
DR   PIRSF; PIRSF036402; Ureas_acces_UreE; 1.
DR   SMART; SM00988; UreE_N; 1.
DR   SUPFAM; SSF69287; SSF69287; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Nickel; Nickel insertion.
FT   CHAIN           1..159
FT                   /note="Urease accessory protein UreE"
FT                   /id="PRO_0000223454"
SQ   SEQUENCE   159 AA;  17592 MW;  362146808B5440F7 CRC64;
     MIRFTQVINS EGRDNFTDRE NCLIVCLTMD ERTKSRLKVC LNNGDEAGLF LPRGTVLKEG
     DLLQAETGEI ALVEAAEEVV STAFTDDLLL LAKACYHLGN RHVPLQVELG WCRYLHDHVL
     DDMVKGLGLG VRVERAKYQP EPGAYGGSIS GASHGHHHH